Extended culture enhances sensitivity of a gamma interferon assay for latent Mycobacterium tuberculosis infection.

نویسندگان

  • Ana Cehovin
  • Jacqueline M Cliff
  • Philip C Hill
  • Roger H Brookes
  • Hazel M Dockrell
چکیده

To test the hypothesis that prolonged culture would enhance the sensitivity of latent tuberculosis detection by a gamma interferon release assay, blood samples from 33 household contacts of Gambian tuberculosis patients were stimulated with Mycobacterium tuberculosis-specific antigens. After 24 h of culture, 66% were positive, compared to 93% after 6 days of culture.

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عنوان ژورنال:
  • Clinical and vaccine immunology : CVI

دوره 14 6  شماره 

صفحات  -

تاریخ انتشار 2007